CAPTURE OF RNA-BINDING PROTEINS ACROSS MOUSE TISSUES USING HARD-AP

Capture of RNA-binding proteins across mouse tissues using HARD-AP

Abstract RNA-binding proteins (RBPs) modulate all aspects of RNA metabolism, but a comprehensive picture of RBP expression across tissues is lacking.Here, we describe our development of the method we call HARD-AP Champion that robustly retrieves RBPs and tightly associated RNA regulatory complexes from cultured cells and fresh tissues.We successful

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Facial palsy after administration of immune checkpoint inhibitors: case report, literature review and clinical care management

Neurological immune-related adverse events (irAEs) due to immune checkpoint inhibitors (ICI) are rare complications of immunotherapy, particularly dreadful for patients and clinical teams.Indeed, neurological irAEs are potentially severe and their diagnosis require prompt recognition and treatment.Additionally, the AAKG spectrum of neurological irA

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